Anti-biofilm Activity of Epigallocatechin gallate (EGCG) against Streptococcus mutans bacteria

Dental caries is a disease caused by Streptococcus mutans. The use of chlorhexidine to inhibit bacterial colonization has side effects such as tooth staining and can kill the normal flora when used long term. Epigallocatechin gallate (EGCG) chemical compound in form polyphenols from green tea catechins which have antimicrobial potency microorganism growth biofilm formation. Type Laboratory Experimental Research In-vitro. group that will be studied are negative control S.mutans + 5% sucrose, treatment S. mutans sucrose EGCG concentration 0.125mg/ml, 0.25mg/ml, 0.375mg/ml positive 0.1% chlorhexidine. Data were analyzed using Kolmogorov-Smirnov test determine normality data, Levene's for homogeneity One Way ANOVA Post Hoc Tukey HSD Multiple Comparison differences between treatments. Results: There significant groups at results with given (p <0.05). influence on activity formation more effective an antibiofilm compared 0.1%.